has part has part has_part primary active transmembrane transporter activity ATP hydrolysis activity ATPase-coupled transmembrane transporter activity https://github.com/geneontology/go-ontology/issues/14642 https://github.com/geneontology/go-ontology/issues/17373 https://github.com/geneontology/go-ontology/issues/19965 https://github.com/geneontology/go-ontology/issues/30193 Reactome:R-HSA-9750546 ATP-dependent transmembrane transporter activity P-P-bond-hydrolysis-driven transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. Reactome:R-HSA-9753278 GO:0015405 Reactome:R-HSA-2161538 P-P-bond-hydrolysis-driven transporter Reactome:R-HSA-9659680 EC:7.2.2.- GO:0042626 ATPase activity, coupled to movement of substances Reactome:R-HSA-9759461 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Reactome:R-HSA-9033505 Reactome:R-HSA-1467457 Reactome:R-HSA-9753283 Reactome:R-HSA-9753284 GO:0016820 Reactome:R-HSA-2161506 Reactome:R-HSA-9750617 molecular_function Reactome:R-HSA-9794572 Reactome:R-HSA-390393 Reactome:R-HSA-9033499 Reactome:R-HSA-9794120 ATPase activity, coupled to transmembrane movement of substances Reactome:R-HSA-9759454 ATP-coupled transmembrane transporter activity ATP-dependent activity