inflammatory response pyroptotic inflammatory response https://github.com/geneontology/go-ontology/issues/27753 biological_process GO:0070269 Reactome:R-HSA-5620971 A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. pyroptosis