regulates (processual) regulates regulates regulation of signal transduction regulation of nervous system process regulation of membrane potential regulation of biological process inhibitory postsynaptic potential modulation of inhibitory postsynaptic potential Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. GO:0098828 regulation of inhibitory postsynaptic potential biological_process