decreased susceptibility to infection decreased susceptibility to prion infection MP:0003003 MPheno.ontology reduced likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is a major and necessary component resistance to prion infection MP:0005363 reduced susceptibility to prion infection abnormal susceptibility to prion infection