<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MP?iri=http://purl.obolibrary.org/obo/MP_0008079"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:mp-edit="http://purl.obolibrary.org/obo/mp-edit#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mp-edit#Sanger_Terms"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mp-edit#Europhenome_Terms"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mp-edit#IMPC"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
        <rdfs:label>has_part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000625 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000625">
        <rdfs:label>CD8-positive, alpha-beta T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0008077 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0008077">
        <rdfs:label>abnormal CD8-positive, alpha-beta T cell number</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0008079 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0008079">
        <rdfs:label>decreased CD8-positive, alpha-beta T cell number</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0001997"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000625"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0008077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0012765"/>
        <oboInOwl:hasExactSynonym>decreased CD8-positive T cell number</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MP:0008079</oboInOwl:id>
        <oboInOwl:hasExactSynonym>reduced CD8+ T cell number</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reduced CD8-positive T cell number</oboInOwl:hasExactSynonym>
        <rdfs:comment>Generally, when immunologists write CD8 positive T cell, what they mean is CD8-positive, alpha-beta T cell (CL:0000625).  Similarly, when immunologists write CD4 positive T cell, what they mean is CD4-positive, alpha-beta T cell (CL:0000624).  T cells bearing the alpha-beta T cell receptor are the most common in the body, and are the most commonly studied, so much so, that in many published papers, the authors do not even bother to specify (or assume) they are studying alpha-beta T cells and thus omit saying so.</rdfs:comment>
        <oboInOwl:hasExactSynonym>decreased CD8+ T cell number</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions</ns4:IAO_0000115>
        <oboInOwl:hasOBONamespace>MPheno.ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#Europhenome_Terms"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#IMPC"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#Sanger_Terms"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0012765 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0012765">
        <rdfs:label>decreased alpha-beta T cell number</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001997 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001997">
        <rdfs:label>decreased amount</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



