<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MP?iri=http://purl.obolibrary.org/obo/MP_0010090"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:mp-edit="http://purl.obolibrary.org/obo/mp-edit#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mp-edit#Sanger_Terms"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mp-edit#IMPC"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
        <rdfs:label>has_part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/GO_0002185 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0002185">
        <rdfs:label>creatine kinase complex</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0010089 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0010089">
        <rdfs:label>abnormal circulating creatine kinase level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0010090 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0010090">
        <rdfs:label>increased circulating creatine kinase level</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000470"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom>
                                    <Class>
                                        <intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002185"/>
                                            <Restriction>
                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                                            </Restriction>
                                        </intersectionOf>
                                    </Class>
                                </someValuesFrom>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0010089"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0014450"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0020280"/>
        <oboInOwl:hasExactSynonym>elevated circulating CK level</oboInOwl:hasExactSynonym>
        <ns5:IAO_0000115>an elevation in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>elevated circulating creatine phosphokinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating CK level</oboInOwl:hasExactSynonym>
        <rdfs:comment>There is ambiguity in the literature regarding the terms creatinine kinase and creatine kinase. Most resources insist that creatine kinase is correct. See PMID:17174558 and PMID:14624200 not to mention Wikipedia. Creatine kinase is an enzyme found in the heart, brain, skeletal muscle, and other tissues. Increased amounts of CK are released into the blood when there is muscle damage. The small amount of CK that is normally in the blood comes primarily from skeletal muscles.</rdfs:comment>
        <oboInOwl:hasExactSynonym>increased circulating creatine phosphokinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>elevated circulating phospho-creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>elevated circulating CPK level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating phospho-creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>MPheno.ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym>elevated circulating creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MP:0010090</oboInOwl:id>
        <oboInOwl:hasExactSynonym>elevated circulating creatinine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating CPK level</oboInOwl:hasExactSynonym>
        <oboInOwl:created_by>csmith</oboInOwl:created_by>
        <oboInOwl:hasExactSynonym>increased circulating creatinine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:creation_date>2010-03-29T12:56:45Z</oboInOwl:creation_date>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#IMPC"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#Sanger_Terms"/>
        <dcterms:contributor rdf:resource="https://orcid.org/0000-0003-3691-0324"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0014450 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0014450">
        <rdfs:label>increased circulating enzyme level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0020280 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0020280">
        <rdfs:label>increased creatine kinase level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000470 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000470">
        <rdfs:label>increased amount</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Individuals
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- https://orcid.org/0000-0003-3691-0324 -->

    <NamedIndividual rdf:about="https://orcid.org/0000-0003-3691-0324">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    </NamedIndividual>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



