<?xml version="1.0"?>
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     xml:base="http://www.w3.org/2002/07/owl"
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     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:mp-edit="http://purl.obolibrary.org/obo/mp-edit#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


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    //
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    <AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
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    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
        <rdfs:label>has_part</rdfs:label>
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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

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        <rdfs:label>has modifier</rdfs:label>
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/GO_0002185 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0002185">
        <rdfs:label>creatine kinase complex</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0010089 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0010089">
        <rdfs:label>abnormal circulating creatine kinase level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0010091 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0010091">
        <rdfs:label>decreased circulating creatine kinase level</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0001997"/>
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                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
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                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0010089"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0014451"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0020281"/>
        <oboInOwl:hasExactSynonym>decreased circulating CK level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>decreased circulating creatine phosphokinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>decreased circulating CPK level</oboInOwl:hasExactSynonym>
        <oboInOwl:creation_date>2010-03-29T12:56:51Z</oboInOwl:creation_date>
        <oboInOwl:hasExactSynonym>reduced circulating CK level</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MP:0010091</oboInOwl:id>
        <ns5:IAO_0000115>a reduction in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>decreased circulating creatinine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reduced circulating creatinine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reduced circulating creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>MPheno.ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:created_by>csmith</oboInOwl:created_by>
        <oboInOwl:hasExactSynonym>reduced circulating phospho-creatine kinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reduced circulating CPK level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reduced circulating creatine phosphokinase level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>decreased circulating phospho-creatine kinase level</oboInOwl:hasExactSynonym>
        <rdfs:comment>There is ambiguity in the literature regarding the terms creatinine kinase and creatine kinase. Most resources insist that creatine kinase is correct. See PMID:17174558 and PMID:14624200 not to mention Wikipedia. Creatine kinase is an enzyme found in the heart, brain, skeletal muscle, and other tissues. Increased amounts of CK are released into the blood when there is muscle damage. The small amount of CK that is normally in the blood comes primarily from skeletal muscles.</rdfs:comment>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#IMPC"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mp-edit#Sanger_Terms"/>
        <dcterms:contributor rdf:resource="https://orcid.org/0000-0003-3691-0324"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0014451 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0014451">
        <rdfs:label>decreased circulating enzyme level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0020281 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0020281">
        <rdfs:label>decreased creatine kinase level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001997 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001997">
        <rdfs:label>decreased amount</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
    


    <!-- 
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    //
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    <!-- https://orcid.org/0000-0003-3691-0324 -->

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        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    </NamedIndividual>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



