has part has part has_part occurs in occurs in characteristic of part of has modifier migratory cranial neural crest cell cell migration abnormal neural crest cell migration abnormal cranial neural crest cell migration abnormal cephalic NCC migration MPheno.ontology abnormal head neural crest cell migration abnormal head NCC migration abnormal cephalic neural crest cell migration any anomaly in the migratory path of the cranial neural crest cells (NCCs), which originate in the anterior part of the developing embryo and reside between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordial; like their counterparts in the trunk, cranial NCCs contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage 2014-04-09T16:15:56Z MP:0012757 csmith abnormal cranial NCC migration quality abnormal