abnormal circulating enzyme level abnormal circulating tartrate resistant acid phosphatase 5b level 2026-06-17T19:23:55Z MP:0015042 any anomaly in the blood of the amount of tartrate resistant acid phosphatase 5b, this isoform of the enzyme is secreted specifically by active osteoclasts during bone resporption total TRAP also includes a macrophage-derived isoform (5a) abnormal circulating tartrate-tesistant acid phosphatase 5b level abnormal serum TRAP5b level