abnormal susceptibility to infection abnormal susceptibility to prion infection 2014-04-30T00:00:00Z nvasilevsky MPheno.ontology altered susceptibility to prion infection altered likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is a major and necessary component MP:0020187