<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MP?iri=http://purl.obolibrary.org/obo/MP_0031220"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
        <rdfs:label>has_part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label>has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MP_0014495 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0014495">
        <rdfs:label>increased circulating chemokine level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0031218 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0031218">
        <rdfs:label>abnormal circulating CXCL10 level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0031220 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0031220">
        <rdfs:label>increased circulating CXCL10 level</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000470"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom>
                                    <Class>
                                        <intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PR_000006064"/>
                                            <Restriction>
                                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                                            </Restriction>
                                        </intersectionOf>
                                    </Class>
                                </someValuesFrom>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0014495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0031218"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0031226"/>
        <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-12-22T11:29:23Z</dc:date>
        <oboInOwl:hasExactSynonym>increased circulating IP-10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating IFN gamma-inducible protein 10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>MPheno.ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym>increased circulating C-X-C motif chemokine ligand 10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating IP10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MP:0031220</oboInOwl:id>
        <oboInOwl:hasExactSynonym>increased circulating small-inducible cytokine B10 level</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>elevation in the blood levels of CXCL10 protein, a pro-inflammatory cytokine that is secreted by a wide range of cell types in response to interferon-gamma, and produces its effects by binding to the cell surface chemokine receptor CXCR3; this chemokine is involved in a variety of processes including chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects, and plays an important role during viral infections by stimulating the activation and migration of immune cells to infected sites</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>increased circulating interferon gamma-induced protein 10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>increased circulating gamma-IP10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>elevated circulating CXCL10 level</oboInOwl:hasExactSynonym>
        <dc:creator rdf:resource="https://orcid.org/0000-0002-6490-7723"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0031226 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0031226">
        <rdfs:label>increased CXCL10 level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000470 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000470">
        <rdfs:label>increased amount</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000006064 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000006064">
        <rdfs:label>C-X-C motif chemokine 10</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Individuals
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- https://orcid.org/0000-0002-6490-7723 -->

    <NamedIndividual rdf:about="https://orcid.org/0000-0002-6490-7723">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    </NamedIndividual>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



