has part has part has_part characteristic of has modifier increased hormone level abnormal angiotensin II level increased angiotensin II level 2020-12-22T13:54:19Z elevated angiotensin II level increased concentration of angiotensin II, a vasoactive octapeptide produced by the action of angiotensin-converting enzyme on angiotensin I; it acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone MP:0031229 MPheno.ontology abnormal increased amount angiotensin II