has part has part has_part characteristic of has modifier part of increased circulating hormone level increased angiotensin II level abnormal circulating angiotensin II level increased circulating angiotensin II level 2020-12-22T14:16:01Z increased serum angiotensin II level elevated circulating angiotensin II level MPheno.ontology increased plasma angiotensin II level MP:0031232 increased concentration in the blood of angiotensin II, a vasoactive octapeptide produced by the action of angiotensin-converting enzyme on angiotensin I; it acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone abnormal increased amount angiotensin II blood