increased chemokine level abnormal CCL3 level increased CCL3 level 2021-03-29T12:10:19Z increased MIP1A level increased macrophage inflammatory protein 1-alpha level increased MIP1-alpha level increased MIP-1alpha level increased MIP-1 alpha level increased C-C motif chemokine 3 level MPheno.ontology MP:0031248 increase in the amount of CCL3 protein, a chemokine that is secreted by a variety of hematopoietic and non-hematopoietic cells upon stimulation and plays a key role in recruiting inflammatory cells (macrophages, lymphocytes, eosinophils and basophils) to sites of injury or inflammation via the CCR1 or CCR5 receptor; it helps promote wound healing by recruiting macrophages to sites of tissue injury; acts as a potent osteoclast activator and induces bone resorption; exerts HIV-suppressive activity; and inhibits hematopoietic stem cell proliferation