abnormal ion homeostasis abnormal bicarbonate homeostasis 2022-04-18T11:32:32Z IUPAC (International Union of Pure and Applied Chemistry)-recommended nomenclature is hydrogencarbonate with the chemical formula CHO3. MPheno.ontology abnormal HCO3- homeostasis anomaly in the processes involved in the maintenance of an internal equilibrium of bicarbonate within the body or between a cell and its external environment; bicarbonate is a polyatomic anion with the chemical formula HCO3- that serves a crucial role in the physiological pH buffering system MP:0031393 abnormal hydrogencarbonate homeostasis