has part has part has_part characteristic of has modifier rough endoplasmic reticulum abnormal endoplasmic reticulum morphology abnormal rough endoplasmic reticulum morphology 2025-10-06T11:11:07Z abnormal granular endoplasmic reticulum morphology any structural anomaly of the form of the endoplasmic reticulum that has ribosomes adhering to its outer surface, giving it a rough appearance The ribosomes adhering to the outer surface of the rough ER are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. MPheno.ontology abnormal RER morphology abnormal rough ER morphology abnormal granular ER morphology MP:0031685 morphology abnormal