abnormal circulating interferon level abnormal circulating interferon type I level 2026-02-18T11:23:34Z Together with IFN-beta, type I IFNs comprise multiple IFN-alpha subtypes (11 in mice and 13 in humans), IFN-epsilon, IFN-kappa, and IFN-omega in most mammals. In addition, IFN-delta, IFN-zeta (limitin), and IFN-tau have been detected exclusively in pigs, mice, and ruminants, respectively. In addition to being induced in response to viruses, they are also produced in immune responses to other classes of pathogens covering bacteria, parasites, and fungi. MP:0031706 MPheno.ontology anomaly in the amount in the blood of any of the cytokines that bind to the IFN-alpha receptor (IFNAR) complex, a heterodimer of IFNAR1 and IFNAR2 chains, and fulfill key functions in anti-viral immunity abnormal circulating IFN type I level abnormal circulating type I IFN level abnormal circulating type I interferon level