tissue specific degenerative process encephalomalacia 2011-11-02T07:43:13Z Areas in the brain where the parenchyma is blanched. Cells in this area are pycnotic. This may be the sequela of an infarction. MPATH:781 Paul Softening of brain tissue, usually caused by vascular insufficiency or degenerative changes. cerebromalacia mouse_pathology.ontology