is about drug-drug interaction effect clinically relevant DDI effect clinical consequences information information about clinical consequences suspected to be the result of a drug-drug interaction An acute hypertensive reaction may be a clinical consequence of epinephrine given in the presence of beta-blockade. An acute upper gastrointestinal bleed or other bleeding event may be a clinical consequence of NSAIDs taken in conjunction with warfarin. An information content entity that is about changes in patient health status from baseline that can be observed or measured by a clinician or reported by a patient and that may be the result of co-administration of two or more drugs that may interact. Boosting of the antiretroviral effect of darunavir is a clinical consequence of co-administration with cobicistat. Changes in patient health status from baseline that can be observed or measured by a clinician or reported by a patient and that may be the result of co-administration of two or more drugs that may interact. https://docs.google.com/viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnxkZGlrcmFuZGlyfGd4OjdhOGVkMzY5MzgxNzkw