Collagenases [Chemical/Ingredient] Microbial Collagenase [Chemical/Ingredient] C0009053 Clostridiopeptidase A D003012 Microbial Collagenase N0000167542 898492 M0004633 collagenase Clostridium histolyticum Nucleolysin Clostridium histolyticum Collagenase Collalysine A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3. Collagenase, Microbial Microbial Collagenase