has role macrolide antibiotic polyene antibiotic amphotericin B (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid 923.488 924.07900 A macrolide antibiotic used to treat potentially life-threatening fungal infections. AMPH-B APKFDSVGJQXUKY-INPOYWNPSA-N Amphotericine B Beilstein:4645978 C47H73NO17 CAS:1397-89-3 CHEBI:106303 CHEBI:2682 CHEBI:566395 DrugBank:DB00681 Drug_Central:197 InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 KEGG:C06573 KEGG:D00203 LIPID_MAPS_instance:LMPK06000002 Liposomal Amphotericin B PMID:11429202 PMID:16120633 PMID:16793999 PMID:1732516 PMID:17507115 Patent:US2908611 Reaxys:4645978 Wikipedia:Amphotericin_B [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 amfotericina B amphotericin B amphotericine B amphotericinum B chebi_ontology bacterial metabolite antibiotic antifungal drug