has part has_part has part peptide antibiotic colistin 1153.742 1169.46050 A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa. C52H97N16O13R CAS:1066-17-7 CAS:1264-72-8 CC[C@@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O CHEBI:34651 CHEBI:37943 CHEBI:472593 CHEBI:560465 CHEBI:566816 CHEBI:596826 CHEBI:597111 CHEBI:600596 CHEBI:659853 Colistin DrugBank:DB00803 KEGG:C13768 KEGG:D02138 PMID:15825037 PMID:16931410 PMID:17145797 PMID:17562800 PMID:17576842 PMID:17606684 PMID:17620384 PMID:17646423 PMID:17846127 PMID:17876007 PMID:18625681 PMID:25322351 PMID:26252512 PMID:26415906 PMID:26488563 PMID:26730548 PMID:27160031 PMID:27411324 PMID:27480806 PMID:27524102 PMID:27552304 PMID:27684296 PMID:27743779 PMID:27790432 PMID:27793510 PMID:27891118 PMID:27917926 PMID:28018876 PMID:28029008 PMID:28215823 PMID:28257552 PMID:28267594 PMID:28267779 PMID:28300674 PMID:28315729 PMID:28321410 chebi_ontology colistina colistine colistinum polymyxin E polymyxin colistin A colistin B