quinolone monocarboxylic acid difloxacin 399.139 399.391 6-fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usually as the monohydrochloride salt) for the treatment of bacterial infections in dogs. C12=C(C(C(C(O)=O)=CN1C3=CC=C(C=C3)F)=O)C=C(F)C(=C2)N4CCN(CC4)C C21H19F2N3O3 CAS:98106-17-3 CHEBI:4537 InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29) KEGG:C11234 KEGG:D07828 NOCJXYPHIIZEHN-UHFFFAOYSA-N PMID:19751946 PMID:22751072 PMID:23742101 PMID:23962048 PMID:25229385 PMID:3800345 Patent:EP131839 Patent:US4730000 Reaxys:5835542 Wikipedia:Difloxacin chebi_ontology difloxacin difloxacine difloxacino difloxacinum N-alkylpiperazine N-arylpiperazine monofluorobenzenes quinolone antibiotic fluoroquinolone antibiotic