has role quinolone quinolinemonocarboxylic acid antimicrobial agent organofluorine compound N-arylpiperazine gatifloxacin 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 375.159 375.39410 A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes. AM 1155 Beilstein:7445861 C19H22FN3O4 CAS:112811-59-3 CHEBI:101712 CHEBI:5280 COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 DrugBank:DB01044 Drug_Central:1280 Gmelin:2281206 InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) KEGG:C07661 KEGG:D08011 LINCS:LSM-5139 PMID:10737746 PMID:12190308 PMID:12620077 PMID:12873512 PMID:12904069 PMID:15125930 PMID:15745831 PMID:15911273 PMID:16078842 PMID:16337791 PMID:16554151 PMID:16759086 PMID:17043111 PMID:17043131 PMID:17064062 PMID:17116666 PMID:17116668 PMID:17157008 PMID:17220425 PMID:17261623 PMID:17276057 PMID:17296740 PMID:17325221 PMID:17387152 PMID:17804222 PMID:17933535 PMID:17960928 PMID:18078756 PMID:18304818 PMID:26963935 PMID:7473575 Patent:EP230295 Patent:US4980470 Reaxys:7445861 Wikipedia:Gatifloxacin XUBOMFCQGDBHNK-UHFFFAOYSA-N chebi_ontology gatifloxacin gatifloxacine gatifloxacino gatifloxacinum quinolone antibiotic