benzophenones catechols tolcapone (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone 273.064 273.24080 3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone 3,4-dihydroxy-5-nitro-4'-methylbenzophenone 4'-methyl-3,4-dihydroxy-5-nitrobenzophenone Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase. C14H11NO5 CHEBI:63630 CHEBI:9617 Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O DrugBank:DB00323 Drug_Central:2697 InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3 KEGG:D00786 LINCS:LSM-5282 MIQPIUSUKVNLNT-UHFFFAOYSA-N PMID:20381177 PMID:20502133 PMID:21521027 PMID:22136163 Patent:EP237929 Patent:US5236952 Reaxys:8151577 Wikipedia:Tolcapone chebi_ontology tolcapone 2-nitrophenols