has role dihydroxybenzoic acid monocarboxylic acid amide antimicrobial agent polycyclic cage cyclic ether cyclic ketone aromatic amide platensimycin (-)-platensimycin 3-({3-[(1S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-1,2,5,6,7,8,9,9a-octahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid 441.179 441.47370 A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the oxatetracyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase. C24H27NO7 CAS:835876-32-9 CHEBI:68236 CSOMAHTTWTVBFL-OFBLZTNGSA-N DrugBank:DB08407 InChI=1S/C24H27NO7/c1-22(7-6-17(28)25-18-14(26)4-3-13(19(18)29)21(30)31)16(27)5-8-24-10-12-9-15(20(22)24)32-23(12,2)11-24/h3-5,8,12,15,20,26,29H,6-7,9-11H2,1-2H3,(H,25,28)(H,30,31)/t12-,15+,20+,22-,23+,24+/m1/s1 KEGG:C20132 PDBeChem:PMN PMID:20158476 PMID:21214253 PMID:21808805 PMID:21915133 PMID:23373732 Patent:CA2770486 Patent:US2009081673 Reaxys:10740321 Wikipedia:Platensimycin [H][C@]12C[C@@H]3O[C@@]1(C)C[C@@]1(C2)C=CC(=O)[C@@](C)(CCC(=O)Nc2c(O)ccc(C(O)=O)c2O)[C@]31[H] chebi_ontology bacterial metabolite