has role has functional parent cephalosporin organic phosphate antimicrobial agent iminium betaine oxime O-ether thiadiazoles 1,3-thiazole ceftaroline fosamil (6R,7R)-7-({(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl}amino)-3-{[4-(1-methylpyridinium-4-yl)-1,3-thiazol-2-yl]sulfanyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 684.010 684.68500 A cephalosporin that is the N-phospho prodrug of ceftaroline. A broad-spectrum antibiotic, it is active against methicillin-resistant Staphylococcus aureus (MRSA). It is used for the treatment of adults with acute bacterial skin and skin structure infections. C22H21N8O8PS4 CAS:229016-73-3 CHEBI:70718 Drug_Central:4169 InChI=1S/C22H21N8O8PS4/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37)/b26-13-/t14-,19-/m1/s1 PMID:21076711 PMID:21115453 PMID:21115454 PMID:21115455 PMID:21115456 PMID:21162631 PMID:21252841 PMID:21393213 PMID:21482565 PMID:21482566 PMID:21482568 PMID:21482570 PMID:21548186 PMID:21897727 PMID:22058102 PMID:22314524 PMID:22330908 PMID:22354289 PMID:22355258 PMID:22594846 PMID:22779432 PMID:22903949 PMID:22985880 Patent:MX2012003411 Reaxys:9535806 Wikipedia:Ceftaroline_fosamil ZCCUWMICIWSJIX-NQJJCJBVSA-N [H][C@]12SCC(Sc3nc(cs3)-c3cc[n+](C)cc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\c1nsc(NP(O)(O)=O)n1)C([O-])=O ceftarolina fosamilo ceftaroline fosamil ceftarolinum fosamilum chebi_ontology ceftaroline