organic heterotricyclic compound N-alkylpiperazine N-arylpiperazine 3-oxo monocarboxylic acid oxazinoquinoline ofloxacin 361.144 361.36750 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. C18H20FN3O4 CAS:82419-36-1 CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O CHEBI:100146 CHEBI:7731 DrugBank:DB01165 Drug_Central:1981 GSDSWSVVBLHKDQ-UHFFFAOYSA-N HMDB:HMDB0015296 InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25) KEGG:C07321 KEGG:D00453 LINCS:LSM-4370 MetaCyc:CPD-12843 OFLX PMID:11710934 PMID:15008519 PMID:16669862 PMID:19646516 PMID:24497308 PMID:24550337 PMID:7884650 Reaxys:3657947 Wikipedia:Ofloxacin chebi_ontology ofloxacin ofloxacine ofloxacino ofloxacinum quinolone antibiotic fluoroquinolone antibiotic