has role glycoside lignan aromatic ether gamma-lactone benzodioxoles naphthofuran plant metabolite cleistanthins Any of the lignans with a 9-aryl-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl glycoside skeleton originally isolated from Cleistanthus collinus, a toxic deciduous shrub. While all parts of the plant are poisonous, the leaves in particular are used as a suicide poison by young women in rural parts of southern India. Cleistanthins A and B have been particularly associated with the toxicity of the plant, with cleistanthin A being more potent than cleistanthin B. CHEBI:84406 PMID:12870879 PMID:14646474 PMID:15260387 PMID:17212028 PMID:17447300 PMID:18319533 PMID:19942753 PMID:20183701 PMID:20397801 PMID:20871771 PMID:21615057 PMID:21824057 PMID:21992915 PMID:22787347 PMID:22923957 PMID:24237798 PMID:25040437 chebi_ontology