has role monocarboxylic acid antimicrobial agent amino acid azabicycloalkane difluorobenzene primary amino compound tertiary amino compound 1,8-naphthyridine derivative quinolone antibiotic fluoroquinolone antibiotic trovafloxacin 416.110 416.35330 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure. C20H15F3N4O3 CAS:147059-72-1 CHEBI:9763 DrugBank:DB00685 Drug_Central:2777 HMDB:HMDB0014823 InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+ KEGG:C07664 KEGG:D08654 N[C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F PMID:20022474 PMID:20462743 PMID:20538741 PMID:20655887 PMID:21151465 PMID:22305082 PMID:23727874 PMID:24097668 PMID:24525298 Reaxys:8172628 WVPSKSLAZQPAKQ-CDMJZVDBSA-N Wikipedia:Trovafloxacin chebi_ontology trovafloxacin trovafloxacine trovafloxacino trovafloxacinum