pyrroline lactam macrolide antibiotic macrolide secondary alcohol cyclic ketone 1,3-oxazoles enamide pristinamycin IIA (3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone 525.248 525.59340 A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. C28H35N3O7 CAS:21411-53-0 CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c2coc(CC(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@H]1C)n2 CHEBI:46395 CHEBI:9997 DAIKHDNSXMZDCU-FQTGFAPKSA-N DrugBank:DB01669 InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1 KEGG:C11299 Mikamycin A Ostreogrycin a PDBeChem:VIR PMID:15480455 PMID:24324222 PMID:24687494 PMID:25223995 PMID:3096930 PMID:5905315 Reaxys:71867 Streptogramin A Virginiamycin M1 Virginiamycin factor M1 Wikipedia:Pristinamycin_IIA chebi_ontology