glucose-6-phosphate dehydrogenase activity 6-phosphoglucose dehydrogenas 6-phosphoglucose dehydrogenase activity Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+. D-glucose 6-phosphate dehydrogenase activity D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity EC:1.1.1.49 Entner-doudoroff enzyme G6PD activity G6PDH GDH GO:0004345 MetaCyc:GLU6PDEHYDROG-RXN NADP-dependent glucose 6-phosphate dehydrogenase activity NADP-glucose-6-phosphate dehydrogenase activity RHEA:15844 Reactome:REACT_102558 Reactome:REACT_104275 Reactome:REACT_112685 Reactome:REACT_114196 Reactome:REACT_114740 Reactome:REACT_1868 Reactome:REACT_28663 Reactome:REACT_29982 Reactome:REACT_31126 Reactome:REACT_33226 Reactome:REACT_33546 Reactome:REACT_34758 Reactome:REACT_80140 Reactome:REACT_83159 Reactome:REACT_84676 Reactome:REACT_87680 Reactome:REACT_89131 Reactome:REACT_90405 Zwischenferment glucose 6-phosphate dehydrogenase (NADP) activity glucose-6-phosphate 1-dehydrogenase activity molecular_function zwischenferment