phosphodiesterase I activity 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity 5'-NPDase activity 5'-PDE activity 5'-PDase activity 5'-exonuclease activity 5'-nucleotide phosphodiesterase activity 5'-phosphodiesterase activity 5'NPDE activity Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides. EC:3.1.4.1 GO:0004528 MetaCyc:3.1.4.1-RXN PDE I activity alkaline phosphodiesterase activity exonuclease I activity molecular_function nucleotide pyrophosphatase/phosphodiesterase I activity oligonucleate 5'-nucleotidohydrolase activity orthophosphoric diester phosphohydrolase activity phosphodiesterase activity