peptide metabolic process cellular modified amino acid metabolic process glutathione metabolic process glutathione biosynthetic process GO:0006750 MetaCyc:GLUTATHIONESYN-PWY Reactome:REACT_103397 Reactome:REACT_105261 Reactome:REACT_110421 Reactome:REACT_110743 Reactome:REACT_32911 Reactome:REACT_33459 Reactome:REACT_6960 Reactome:REACT_81322 Reactome:REACT_82189 Reactome:REACT_84374 Reactome:REACT_85658 Reactome:REACT_88522 Reactome:REACT_90769 Reactome:REACT_92740 Reactome:REACT_94932 Reactome:REACT_96555 Reactome:REACT_97813 Reactome:REACT_98722 The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. biological_process glutathione anabolism glutathione biosynthesis glutathione formation glutathione synthesis sulfur compound metabolic process metabolic process