<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/NCIT?iri=http://purl.obolibrary.org/obo/NCIT_C12536"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P322"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P366"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P325"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P106"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_NHC0"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P107"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P108"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P207"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/NCIT_C116977 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C116977">
        <rdfs:label>CTRP Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C12536 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C12536">
        <rdfs:label>Natural Killer Cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C39568"/>
        <ns3:NCIT_P325>A type of immune cell that has granules (small particles) with enzymes that can kill tumor cells or cells infected with a virus. A natural killer cell is a type of white blood cell.</ns3:NCIT_P325>
        <ns3:NCIT_P108>Natural Killer Cell</ns3:NCIT_P108>
        <oboInOwl:hasExactSynonym>killer cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NK Cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NK</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P366>Natural_Killer_Cell</ns3:NCIT_P366>
        <ns3:NCIT_P322>CDISC</ns3:NCIT_P322>
        <oboInOwl:hasExactSynonym>NATURAL KILLER CELL</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Natural Killer Cell</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P325>Cells resembling large granular lymphocytes that do not express markers of either T or B cell lineage. These cells express Fc receptors for IgG and can kill target cells using antibody-dependent cell-mediated cytotoxicity. They can also use perforin to kill cells in the absence of antibody, and may occur without previous sensitization.</ns3:NCIT_P325>
        <ns3:IAO_0000115>Natural killer cells are cells that resemble large granular lymphocytes.  They do not express markers of either T or B cell lineage. They are positive for CD16, CD56, and CD 94.  These cells do possess Fc receptors for IgG and can kill target cells using antibody-dependent cell-mediated cytotoxicity. They can also use perforin to kill cells in the absence of antibody and killing may occur without previous sensitization.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Killer Cells</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P106>Cell</ns3:NCIT_P106>
        <ns3:NCIT_P107>Natural Killer Cell</ns3:NCIT_P107>
        <oboInOwl:hasExactSynonym>natural killer cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Killer Cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NK-LGL</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NK-Cell</oboInOwl:hasExactSynonym>
        <ns3:NCIT_NHC0>C12536</ns3:NCIT_NHC0>
        <ns3:NCIT_P322>CTRP</ns3:NCIT_P322>
        <oboInOwl:hasExactSynonym>NK cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NK Cells</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P207>C0022688</ns3:NCIT_P207>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C116977"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C142799"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C61410"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C66830"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C78734"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C142799 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C142799">
        <rdfs:label>CTRP Biomarker Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C39568 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C39568">
        <rdfs:label>Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C61410 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C61410">
        <rdfs:label>Clinical Data Interchange Standards Consortium Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C66830 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C66830">
        <rdfs:label>CDISC SDTM Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C78734 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C78734">
        <rdfs:label>CDISC SDTM Specimen Type Terminology</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



