Disease_Has_Molecular_Abnormality Disease_May_Have_Finding Disease_Excludes_Finding Disease_May_Have_Molecular_Abnormality CTRP Terminology CTRP Disease Terminology TET2 Gene Mutation DNMT3A Gene Mutation Age-Related Clonal Hematopoiesis Clonal Hematopoiesis of Indeterminate Potential Clonal Hematopoiesis of Indeterminate Potential C158547 CTRP Clonal Hematopoiesis of Indeterminate Potential CL937953 A term that refers to the presence of somatic mutations in bone marrow or peripheral blood cells in individuals who may be cytopenic but do not have morphologic evidence of hematologic neoplasia. Its prevalence rises with age and is found in approximately 10% of individuals aged 70 to 80. It is associated with an increased risk of hematologic neoplasia. Mutations in the DNMT3A, TET2, or ASXL1 genes are usually identified. Approximately 10%-40% of individuals with age-related clonal hematopoiesis will progress to meet the diagnostic criteria for clonal hematopoiesis of indeterminate potential. CHIP Disease or Syndrome Clonal Hematopoiesis of Indeterminate Potential Clonal Hematopoiesis Somatic Variation Cytopenia Malignant Cellular Infiltrate DNMT3A Gene TET2 Gene ASXL1 Gene Mutation ASXL1 Gene