BRIDG Terminology BRIDG Class Terminology Gene Gene Genes The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein. A functional unit of heredity that occupies a specific position (locus) on a particular chromosome, is capable of reproducing itself exactly at each cell division, and directs the formation of a protein or other product. Comment Requested: In interest of re-using existing standards, should the above definition of Gene be replaced by the following from the NLM - The basic physical and functional unit of heredity. It is made up of DNA and act as instructions to make molecules called proteins. [Source: http://ghr.nlm.nih.gov/handbook/basics/gene] EXAMPLE(S): BRCA1 gene OTHER NAME(S): NOTE(S): BRIDG Gene or Genome Gene gene A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. The gene as a functional unit consists of a discrete segment of a giant DNA molecule containing the purine (adenine and guanine) and pyrimidine (cytosine and thymine) bases in the ordered and correct sequence that encodes a specific functional product (i.e., a protein or RNA molecule). C16612 C0017337 Gene Biological Process Drug, Food, Chemical or Biomedical Material Diagnostic or Prognostic Factor Conceptual Entity Property or Attribute Biochemical Pathway Experimental Organism Diagnosis Experimental Organism Anatomical Concept Gene Product Retired Concept Molecular Abnormality Activity Disease, Disorder or Finding Manufactured Object