<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/NCIT?iri=http://purl.obolibrary.org/obo/NCIT_C34786"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P322"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P366"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P375"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P325"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P106"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_NHC0"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P108"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P207"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/NCIT_C101852 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C101852">
        <rdfs:label>CDISC SDTM Sudden Death Syndrome Type Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C118464 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C118464">
        <rdfs:label>Pediatric Adverse Events Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C165258 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C165258">
        <rdfs:label>Cellosaurus Disease Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C189762 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C189762">
        <rdfs:label>Pediatric Adverse Events Terminology Mapped to MedDRA</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C28193 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C28193">
        <rdfs:label>Syndrome</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C34786 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C34786">
        <rdfs:label>Long QT Syndrome</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C28193"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C35741"/>
        <ns3:NCIT_P325>Long QT Syndrome includes prolongation of the corrected QT interval beyond 440 ms for adult males, 460 ms for adult females and 50 ms in the presence of ventricular depolarization abnormalities (i.e., bundle branch blocks or IVCB more than 120 ms. A normal QT interval in a resting ECG with a failure to shorten with an increase in heart rate qualifies as Long QT Syndrome.</ns3:NCIT_P325>
        <ns3:NCIT_P322>NICHD</ns3:NCIT_P322>
        <ns3:NCIT_P366>Long_QT_Syndrome</ns3:NCIT_P366>
        <oboInOwl:hasExactSynonym>Ventricular arrhythmia associated with long QT syndrome</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P322>MedDRA</ns3:NCIT_P322>
        <ns3:NCIT_P207>C3809224</ns3:NCIT_P207>
        <ns3:NCIT_NHC0>C34786</ns3:NCIT_NHC0>
        <ns3:NCIT_P322>Cellosaurus</ns3:NCIT_P322>
        <ns3:NCIT_P325>A syndrome characterized by a propensity to develop life-threatening arrhythmias usually in the context of a prolonged corrected QT interval.</ns3:NCIT_P325>
        <ns3:NCIT_P375>Long QT syndrome</ns3:NCIT_P375>
        <ns3:NCIT_P108>Long QT Syndrome</ns3:NCIT_P108>
        <ns3:IAO_0000115>A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>LONG QT SYNDROME</oboInOwl:hasExactSynonym>
        <ns3:NCIT_P106>Disease or Syndrome</ns3:NCIT_P106>
        <ns3:NCIT_P322>CDISC</ns3:NCIT_P322>
        <oboInOwl:hasExactSynonym>Long QT Syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C101852"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C118464"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C165258"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C189762"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C61410"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C66830"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C90259"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/NCIT_C99147"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C35741 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C35741">
        <rdfs:label>Non-Neoplastic Heart Disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C61410 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C61410">
        <rdfs:label>Clinical Data Interchange Standards Consortium Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C66830 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C66830">
        <rdfs:label>CDISC SDTM Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C90259 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C90259">
        <rdfs:label>NICHD Terminology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C99147 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C99147">
        <rdfs:label>Neonatal Research Network Terminology</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



