Macular Degeneration Cellosaurus Disease Terminology Age-Related Macular Degeneration C4230251 A condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive layers of nerve tissue at the back of the eye). This blocks vision in the center of the eye and can cause problems with activities such as reading and driving. Age-related macular degeneration is most often seen in people who are over the age of 50. Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. Disease or Syndrome Cellosaurus Age-Related Macular Degeneration AMD Age-Related Macular Degeneration C84391 ARMD age-related macular degeneration