occurs in has participant quality edema AE periorbital edema AE NCIt: C78530 Periorbital puffiness, also known as "puffy eyes" or swelling around the eyes, refers to the appearance of swelling in the tissues around the eyes, called the orbits. WEB: http://en.wikipedia.org/wiki/Periorbital_puffiness CTCAE: E13676 UMLS CUI: C0151205 periorbital oedema AE SS, YH periorbital puffiness MedDRA: 10034545 is for "periorbital edema"; MedDRA: 10054541 is for "periorbital oedema" periorbial edema AE is an edema AE that has an outcome of swelling around the eye. AE severity G1 AE severity G2 AE severity G3 eye