cardiac valve disease AE papillary muscle disorder AE 10061330 WEB: http://medical-dictionary.thefreedictionary.com/papillary+muscle+dysfunction a cardiac valve disease AE that is characterized by an impaired function of a papillary muscle, usually due to ischemia or infarction, with resulting incompetence of the mitral (rarely tricuspid) valve. SS papillary muscle syndrome papillary muscle dysfunction