abnormal reflex AE hyperreflexia AE WEB: https://en.wikipedia.org/wiki/Hyperreflexia SIDER: C0151889 HPO: HP_0001347 10020745 JX, YH an abnormal reflex AE that has an outcome of overactive reflexes, indicative of upper motor neuron disease as well as lessening or loss of control ordinarily exerted by higher brain centers of lower neural pathways.