has participant quality electrocardiogram qt prolonged AE AE severity G4 Grade 4 electrocardiogram qt prolonged AE CTCAE: E12150 an electrocardiogram qt prolonged AE where the QTc is greater than or equal to 501 or greater than 60 ms change from baseline and Torsade de pointes or polymorphic ventricular tachycardia or signs/symptoms of serious arrhythmia MW, YH