granuloma AE chronic granulomatous disease AE 10008906 http://en.volupedia.org/wiki/Chronic_granulomatous_disease This is an AE which is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. QY, JX, HY 慢性肉芽肿性疾病