bone lesion AE osteopetrosis AE 骨硬化病 10031280 QY, JX, HY This is an AE which is an extremely rare inherited disorder whereby the bones harden, becoming denser, in contrast to more prevalent conditions like osteoporosis, in which the bones become less dense and more brittle, or osteomalacia, in which the bones soften. Osteopetrosis can cause bones to dissolve and break. http://en.volupedia.org/wiki/Osteopetrosis