scleroderma AE systemic scleroderma AE 系统性硬皮病 http://en.volupedia.org/wiki/Systemic_scleroderma QY, JX, HY This is an AE which is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. 10078638