part of part of develops_from midgut caecum vermiform appendix A comparative anatomical approach reveals three apparent morphotypes of the cecal appendix, as well as appendix-like structures in some species that lack a true cecal appendix. Cladistic analyses indicate that the appendix has evolved independently at least twice (at least once in diprotodont marsupials and at least once in Euarchontoglires), shows a highly significant (P < 0.0001) phylogenetic signal in its distribution, and has been maintained in mammalian evolution for 80 million years or longer.[well established][VHOG] BTO:0000084 appendix vermiformis MAT:0000287 OpenCyc:Mx4rvVjGgJwpEbGdrcN5Y29ycA MIAA:0000287 EV:0100076 appendix galen:AppendixVermiformis cecal appendix MA:0001540 vermix Organ with organ cavity which is continuous proximally with the cecum and distally terminates in the tip of the appendix. Examples: There is only one appendix[FMA:14542]. appendix vermiformis EMAPA:35140 uberon apex of caecum appendiceal GAID:308 UBERON:0001154 VHOG:0001306 A blind-ended tube connected to the cecum, from which it develops embryologically[WP]. CALOHA:TS-1267 EFO:0000849 apex of cecum EHDAA2:0000588 MESH:A03.492.411.495.209.290 FMA:14542 caecal appendix UMLS:C0003617 EV:0100080 lower digestive tract digestive system element