part of part of develops_from contributes to morphology of immediate transformation of brain forebrain prosencephalic DMBA:15566 EHDAA:3470 BAMS:Forebrain EFO:0000909 VHOG:0000383 Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO] MAT:0000105 AAO:0010147 BTO:0000478 TAO:0000109 In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG] The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO] uberon relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO] UMLS:C0085140 EHDAA2:0000556 MIAA:0000105 prosencephalon FMA:61992 ZFA:0000109 The most anterior region the brain including both the telencephalon and diencephalon. http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=27 MESH:D016548 CALOHA:TS-0380 XAO:0000011 EMAPA:16895 BAMS:FB UBERON:0001890 FB MA:0000170 DHBA:10156 regional part of brain anterior neural tube future forebrain