part of part of deep_to superficial_to develops_from composed primarily of mesoderm adipose tissue musculature dermis hypodermis vertebrate hypodermis subcutis A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO] hypodermal UMLS:C0278403 TAO:0001136 superficial fascia subcutaneous uberon FMA:70544 ZFA:0001136 A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]. subcutaneous tissue Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument. sub-tegumental tissue CALOHA:TS-2366 BTO:0001314 tela subcutanea subcutaneus UBERON:0002072 hypoderm subtegumental tissue integument mesoderm-derived structure loose connective tissue integumentary system layer