has part has part bounding layer of surrounded_by existence ends during fully formed stage anatomical system multicellular organism integumental system integumentary system HAO:0000421 integumentum commune EHDAA2_RETIRED:0003154 MIAA:0000033 UBERON:0002416 external covering of organism VHOG:0000403 FMA:72979 EFO:0000807 UMLS:C0037267 galen:Surface EHDAA2:0000836 UBERON:0007029 AEO:0000154 uberon Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. FBbt:00004969 EMAPA:17524 CALOHA:TS-1299 BILA:0000118 dermal system TADS:0000108 body surface EV:0100151 MESH:D034582 CARO:0002001 (...) the integument of many tetrapods is reinforced by a morphologically and structurally diverse assemblage of skeletal elements. These elements are widely understood to be derivatives of the once all-encompassing dermal skeleton of stem-gnathostomes (...).[well established][VHOG] MA:0000014 MAT:0000033 organism surface XAO:0000176 EHDAA:6520 surface outer epithelium space surrounding organism